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(Total 12 Products for 1 H Pyrazole)
Several pyrazole compounds have been reported to have anti-diabetic effects by acting as agonists on PPAR. According to the principle of ligand-receptor interaction reported in the docking study of pyrazole compounds with Ppargamma, this study was extended to the docking study of pyrazole compounds, the pyrazole...
Pyrazole is a colorless solid with boiling point (BP) of 186-188 °C, Melting Point (MP) of 67-70 °C, PKB = 11.5(PKA of conjugated acid is 2.49 at 25 °C, molecular weight Wt. 68.0776 G/mol, soluble in water. Pyrazole was synthesized in one step using glycerol and hydrazine hydrate as dehydrogenation catalyst in...
Historically, heterocyclic compound and their derivatives have been invaluable as sources of therapeutic agents. Pyrazole, which has two nitrogen atoms and two aromatic groups, provides multiple functions and stereochemical complexity in the five-membered ring structure. Over the past decade, more and more data have...
pyrazole and imidazole difference
Pyrazole ring is a prominent structural motif found in many drug-active compounds. This is mainly due to its ease of preparation and pharmacological activity. The selective functionalization of pyrazoles with various substituents has also been found to improve their range of action in various fields. As part of the...
is pyrazole a chemical compound
DNA gyrase is an essential bacterial enzyme involved in DNA replication, transcription and recombination. It belongs to a class of enzymes called topoisomerase that are involved in the topological transformation of DNA. The ATP-dependent negative superhelix of double-stranded closed-loop DNA can be catalyzed by this...
1h-pyrazole-5-boronic acid pinacol ester
Pyrazole and its related polycyclic analogues are common elements in a variety of bioactive compounds. These ring structures are essentially rare. As a result, they were previously thought to be low-molecular-weight components of potential new drugs. However, in recent years, these groups have been widely used in new...
knorr pyrazole synthesis slideshare
Pyrazole, also known as 1,2-diazoles, Diazene Pentacyclines, o-diazepines; is White needle-shaped or prismatic crystal, from ethanol crystallization of pyrazole is colorless needle-shaped crystal. Pyridine-like odor and pungent bitter taste, soluble in water, alcohol, ether and benzene. The boiling point and melting...
knorr pyrazole synthesis applications
Pyrazole can also be used as the side chain of some photosensitive monomers. In addition, Pyrazole is also used as a halogen-containing Solvent, lubricant stabilizer, chelating agent, organic synthesis intermediate. Pyrazole, also known as 1,2-diazoles, Diazene Pentacyclines, o-diazepines; is White needle-shaped or...
pyrazole thiamethoxam bacteria amine
Pyrazole, as an intermediate of some medicine and pesticide, plays an important role in the research and development of medicine and pesticide. More and more attention has been paid to pyrazole compounds because of their broad action spectrum and strong efficacy. In Medical Application, Pyrazole compounds have...
pyrazole or their derivatives occurs in
Pyrazole was synthesized in one step using glycerol and hydrazine hydrate as dehydrogenation catalyst in sulfuric acid by using sodium iodide, which is cheap and easily obtained, and then neutralized by Liquid Alkali to Ph = 7-8, filtered to remove the inorganic salts, the mixed solution was dehydrated by benzene...
why is pyrazole highly soluble in water
Pyrazole compounds are a new kind of pharmaceutical and pesticide intermediates, which are widely used in the fields of pesticide, electronics and medicine. The content of total active ingredient is more than 98.0% , the moisture is less than 0.5% , the appearance is white or yellowish crystal. Pyrazole was...
pyrazole and ethanol metabolism
Owing to several potential applications, the novel design of Pyrazoles, the discovery of novel synthetic routes for Pyrazoles, the study of different potency of pyrazoles and the search for potential applications of pyrazoles are increasing in importance. Pyrazole was synthesized in one step using glycerol and...
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